Description

Disulfiram is an organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties. It has a role as a ferroptosis inducer, a fungicide, an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor, an antineoplastic agent, an EC 3.1.1.8 (cholinesterase) inhibitor, an angiogenesis inhibitor, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, an apoptosis inducer, a NF-kappaB inhibitor and an EC 3.1.1.1 (carboxylesterase) inhibitor. It is an organic disulfide and an organosulfur acaricide.