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Description
HTH-01-015 is an organic heterotetracyclic compound that is 5,13-dihydro-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one substituted by methyl groups at positions 4, 5 and 13, and by a [1-(piperidin-4-yl)-1H-pyrazol-4-yl]amino group at position 2. It is a potent NUAK1 inhibitor (IC50 = 100 nM). It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a member of piperidines, a member of pyrazoles, an aromatic amine, an organic heterotetracyclic compound, a secondary amino compound and a tertiary amino compound.
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- Source creator
- Daniel Navarrete
- Source license
- CC-BY
Archived copies are shared under the license shown.
View/download on NIH 3DTags
#nih-3d
#small molecules
#hth-01-015
#refchem:146873
#1613724-42-7
#hth 01 015
#4,5,13-trimethyl-2-((1-(piperidin-4-yl)-1h-pyrazol-4-yl)amino)-5,13-dihydro-6h-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one
#chembl4303250
#6h-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one, 5,13-dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1h-pyrazol-4-yl]amino]-
#2,7,9-trimethyl-5-[(1-piperidin-4-ylpyrazol-4-yl)amino]-2,4,6,9-tetrazatetracyclo[9.8.0.03,8.013,18]nonadeca-1(19),3,5,7,11,13,15,17-octaen-10-one
#4,5,13-trimethyl-2-{[1-(piperidin-4-yl)-1h-pyrazol-4-yl]amino}-5,13-dihydro-6h-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one
#gtpl8977
#orb1305577
#schembl16065674
#schembl29504101
#c26h28n8o
#chebi:234378
#glxc-05513
#bcp14400
#ex-a1038
#hth01015
#bdbm50587671
#hth01-015
#s7318
#akos026750455
#ccg-269434
#cs-3344
#mfcd28167816
#hth 01-015
#5,13-dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1h-pyrazol-4-yl]amino]-6h-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one
#orb1226056
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d
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