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Description
Low-density lipoprotein receptor-related protein 1B (LRP1B) is a member of the LDL receptor family, and is involved in receptor-mediated endocytosis. It also plays roles in cell migration, tumor suppression, and signal transduction. LRP1B interacts with various intracellular proteins and can participate in signal transduction pathways, impacting processes like cell growth, migration, and DNA damage response. LRP1B is considered a candidate tumor suppressor gene and is frequently inactivated in various cancers, including lung cancer.
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- Source creator
- Jeff Miller
- Source license
- Public Domain
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