Description

Glycogen synthase kinase 3 beta (GSK3B), is a multi-functional serine/threonine kinase that regulates glucose homeostasis, cell signaling, and neuronal function. It typically acts as a negative regulator, often inhibiting various cellular pathways and processes. GSK3B is a key component in various signaling pathways, including the Wnt signaling pathway, where it phosphorylates beta-catenin, leading to its degradation and inhibition of Wnt signaling.