Description

Domoic acid is an L-proline derivative that is L-proline substituted by a carboxymethyl group at position 3 and a 6-carboxyhepta-2,4-dien-2-yl group at position 4. It is produced by the diatomic algal Pseudo-nitzschia. It is an analogue of kainic acid and a neurotoxin which causes amnesic shellfish poisoning (ASP). It has a role as a neurotoxin, a neuromuscular agent, a hapten, a marine metabolite and an algal metabolite. It is a tricarboxylic acid, a pyrrolidinecarboxylic acid, a non-proteinogenic L-alpha-amino acid and a L-proline derivative. It is a conjugate acid of a domoate(2-).