Naltrexone
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Description

Naltrexone is an organic heteropentacyclic compound that is naloxone substituted in which the allyl group attached to the nitrogen is replaced by a cyclopropylmethyl group. A -opioid receptor antagonist, it is used to treat alcohol dependence. It has a role as a central nervous system depressant, a xenobiotic, a mu-opioid receptor antagonist, an environmental contaminant and an antidote to opioid poisoning. It is an organic heteropentacyclic compound, a member of cyclopropanes and a morphinane-like compound. It is a conjugate base of a naltrexone(1+).

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Source creator
Steve Wilson
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CC-BY
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#nih-3d
#small molecules
#naltrexone
#16590-41-3
#vivitrol
#revia
#celupan
#n-cyclopropylmethylnoroxymorphone
#vivitrex
#naltrexona
#nemexin
#17-(cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one
#n-cyclopropylmethyl-14-hydroxydihydromorphinone
#17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
#5s6w795cqm
#chebi:7465
#en-1639a free base
#dtxsid4046313
#nsc-758439
#(4r,4as,7ar,12bs)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
#um-792
#en-1639a [as hydrochloride]
#naltrexonum [inn-latin]
#(1s,5r,13r,17s)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-one
#(4r,4as,7ar)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
#naltrexona [inn-spanish]
#dtxcid2026313
#naltrexonum
#morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5.alpha.)-
#naltrexone [usan:inn:ban]
#naltrexone base anhydrous
#cas-16590-41-3
#ccris 3506
#hsdb 6750
#einecs 240-649-9
#brn 3596648
#unii-5s6w795cqm
#(-)naltrexone
#pti-555
#ncgc00162274-02
#(-)-naltrexone
#vivitrol (tn)
#naltrexone [mi]
#naltrexone [inn]
#(4r,4as,7ar,12bs)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
#naltrexone (usan/inn)
#prestwick0_000116
#prestwick1_000116
#prestwick2_000116
#prestwick3_000116
#naltrexone [hsdb]
#naltrexone [usan]
#naltrexone [vandf]
#morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5alpha)-
#naltrexone [mart.]
#naltrexone [usp-rs]
#naltrexone [who-dd]
#us9107954, naltrexone
#schembl34681
#bspbio_000132
#bidd:gt0405
#chembl19019
#spbio_002071
#bpbio1_000146
#gtpl1639
#zinc1773
#naltrexone [orange book]
#bdbm60212
#cid_5485201
#cyclopropylmethyl(dihydroxy)[?]one
#hms2089o11
#bcp07022
#ex-a4863
#tox21_112007
#bdbm50000787
#mfcd00242996
#pdsp2_000847
#akos015994596
#morphinan-6-one, 17-(cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-
#tox21_112007_1
#cs-0880
#db00704
#hs-0002
#naltrexone component of contrave
#nsc 758439
#smp1_000206
#ncgc00024427-03
#ncgc00024427-04
#ncgc00024427-05
#ac-36726
#hy-76711
#c07253
#d05113
#ab00174152-14
#ab00174152_17
#ar-270/43507956
#en300-19748946
#q409587
#brd-k88172511-003-21-1
#brd-k88172511-310-03-8
#3,14-dihydroxy-17-(cyclopropylmethyl)-4,5alpha-epoxymorphinan-6-one
#17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxmorphinan-6-one, (5.alpha.)-
#(4r,4as,7ar,12bs)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
#(4r,4as,7ar,12bs)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7ah)-one
#(4r,4as,7ar,12bs)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
#4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0~1,13~.0~5,17~.0~7,18~]octadeca-7(18),8,10-trien-14-one
#nalorex
#adepend
#opizone
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d

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Naltrexone

From NIH 3D
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Category

learning

License

CC-BY

Published

8/29/2026

Availability

free on NIH 3D