Pacritinib
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Description

Pacritinib is an azamacrocycle with formula C28H32N4O3. It is a Janus kinase inhibitor and its citrate salt is approved for the treatment of intermediate or high risk, primary or secondary myelofibrosis. It has a role as an antineoplastic agent, an anti-inflammatory agent, an apoptosis inducer and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a member of benzenes, a cyclic ether, a member of pyrrolidines and an azamacrocycle. It is a conjugate base of a pacritinib(1+).

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Glyphosate
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#nih-3d
#small molecules
#pacritinib
#937272-79-2
#pacritinib (sb1518)
#sb1518
#sb-1518
#pacritinib(sb1518)
#unii-g22n65il3o
#g22n65il3o
#onx-0803
#11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene
#sb 1518
#vonjo
#14,19-dioxa-5,7,27-triazatetracyclo(19.3.1.12,6.18,12)heptacosa-1(25),2,4,6(27),8,10,12(26),16,21,23-decaene, 11-(2-(1-pyrrolidinyl)ethoxy)-, (16e)-
#chembl2181330
#pacritinib [inn]
#pacritinib (usan/inn)
#pacritinib [usan:inn]
#pacritinib [usan]
#pacritinib [who-dd]
#sb-1518 tfa salt
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#schembl1108221
#chembl2035187
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#ccg-269464
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#ncgc00381564-02
#ncgc00390623-02
#ac-30280
#as-35036
#hy-16379
#sw219864-1
#d11768
#sb1518;sb-1518;sb 1518
#q3888693
#(16e)-11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaene
#pacritinibum
#11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene
#refchem:58092
#oral jak2 inhibitor sb1518
#dtxcid201527601
#(16e)-11-(2-(pyrrolidin-1-yl)ethoxy)-14,19-dioxa-5,7,27-triazatetracyclo(19.3.1.1^(2,6).1^(8,12))heptacosa-1(25),2(27),3,5,8,10,12(26),16,21,23-decaene
#(16e)-11-[2-(1-pyrrolidinyl)ethoxy]-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2,4,6(27),8,10,12(26),16,21,23-decaene
#c28h32n4o3
#pacritinib [mi]
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d

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Pacritinib

From NIH 3D
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Category

learning

License

CC-BY

Published

8/30/2026

Availability

free on NIH 3D