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Description
Histidine decarboxylase from Lactobacillus 30a was the first pyruvoyl-dependent enzyme reported. Rather than being a vitamin B6 (PLP)-dependent decarboxylase, this protein makes its own prosthetic group by converting an internal serine residue in its proenzyme form into a pyruvoyl group that promotes the decarboxylation of histidine into histamine (PDB 1PYA).
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- Hackprof
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