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Description
Olaparib is a member of the class of N-acylpiperazines obtained by formal condensation of the carboxy group of 2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoic acid with the free amino group of N-(cyclpropylcarbonyl)piperazine; used to treat advanced ovarian cancer. It has a role as an antineoplastic agent, an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an apoptosis inducer. It is a member of phthalazines, a N-acylpiperazine, a member of cyclopropanes and a member of monofluorobenzenes.
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- Source creator
- bejan3D
- Source license
- CC-BY
Archived copies are shared under the license shown.
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#nih-3d
#small molecules
#olaparib
#763113-22-0
#azd2281
#lynparza
#ku-0059436
#azd 2281
#azd-2281
#1-(cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine
#4-(3-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2h)-one
#olaparib (azd2281, ku-0059436)
#olaparib (azd-2281)
#ku-59436
#4-[[3-[4-(cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorophenyl]methyl]-2h-phthalazin-1-one
#az2281
#mfcd13185161
#woh1jd9ar8
#nsc-747856
#c24h23fn4o3
#chebi:83766
#4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2h)-one
#4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2h-phthalazin-1-one
#az-2281
#keylynk-010 component olaparib
#ku59436
#olaparib component of keylynk-010
#olaparib [inn]
#olaparib cpd
#olaparib (azd2281; ku-0059436)
#olaparib [usan:inn]
#unii-woh1jd9ar8
#olaparib (azd2281)
#olaparibum
#azd221
#4-[3-[4-(cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorobenzyl]phthalazin-1(2h)-one
#olaparib- bio-x
#lynparza (tn)
#09l
#4-((3-((4-(cyclopropylcarbonyl)piperazin-1-yl)carbonyl)-4-fluorophenyl)methyl)phthalazin-1(2h)-one
#4-((3-{(4-(cyclopropylcarbonyl)piperazin-1-yl)carbonyl}-4-fluorophenyl)methyl)phthalazin-1(2h)-one
#4-[(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorophenyl)methyl]phthalazin-1(2h)-one
#ku 59436
#olaparib [usan]
#olaparib [jan]
#ku0059436
#olaparib [mi]
#olaparib [vandf]
#olaparib - azd2281
#olaparib [mart.]
#olaparib [who-dd]
#azd-2281 (olaparib)
#olaparib (jan/usan/inn)
#mls006010185
#schembl426568
#olaparib [orange book]
#chembl521686
#gtpl7519
#bdbm27566
#dtxsid60917988
#ex-a002
#bcpp000360
#hms3295i09
#hms3426c03
#hms3654g13
#hms3746k07
#hms3870h03
#amy10295
#bcp01872
#763113-22-0, lynparza,
#nsc747856
#nsc753686
#s1060
#zinc40430143
#akos005145764
#ac-7939
#bcp9000363
#ccg-264799
#cs-0075
#db09074
#ex-7210
#nsc 747856
#nsc-753686
#sb14617
#ss-4573
#azd2281,olaparib, ku-0059436
#ncgc00238451-01
#ncgc00238451-02
#ncgc00238451-08
#ncgc00238451-09
#ncgc00238451-11
#4-[(3-{[4-cyclopropylcarbonyl)piperazin-4-yl]carbonyl}-4-fluorophenyl)methyl]phtalazin-1(2h)-one
#bo164169
#hy-10162
#smr004701291
#sy040527
#olaparib(azd2281,kudosku-0059436)
#a9666
#bb 0260909
#ft-0651458
#ku 0059436
#sw218142-2
#ec-000.2324
#d09730
#j-503540
#q7083106
#brd-k02113016-001-08-9
#brd-k02113016-001-09-7
#1-(cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazine
#4-(3-(1-(cyclopropanecarbonyl)piperazine-4-carbonyl)-4-fluorobenzyl)phthalazin-1(2h)-one
#(2h)-phthalazinone, 4-((3-((4-(cyclopropylcarbonyl)-1-piperazinyl)carbonyl)-4-fluorophenyl)methyl)-
#1(2h)-phthalazinone, 4-((3-((4-(cyclopropylcarbonyl)-1-piperazinyl)carbonyl)-4-fluorophenyl)methyl)-
#1021843-02-6
#4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbonyl]-4-fluorophenyl}methyl)-1,2-dihydrophthalazin-1-one
#piperazine, 1-(cyclopropylcarbonyl)-4-(5-((3,4-dihydro-4-oxo-1-phthalazinyl)methyl)-2-fluorobenzoyl)-
#4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2h)-phthalazinone
#4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one
#en300-7542225
#z2227698469
#4-(3-((4-(cyclopropylcarbonyl)piperazin-1-yl)carbonyl)-4-fluorobenzyl)phthalazin-1(2h)-one
#4-((3-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorophenyl)methyl)-2h-phthalazin-1-one
#4-((3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl)methyl)-1,2-dihydrophthalazin-1-one
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d
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