Description

SARS-CoV-2 spike protein from 6VSB. The protomer that has its Receptor Binding Domain (RBD) flipped into the up (active) conformation has its domains colored as described in Figure 1 of: Wrapp, D. (http://www.rcsb.org/search?q=citation.rcsb_authors:Wrapp,%20D.), Wang, N. (http://www.rcsb.org/search?q=citation.rcsb_authors:Wang,%20N.), Corbett, K.S. (http://www.rcsb.org/search?q=citation.rcsb_authors:Corbett,%20K.S.), Goldsmith, J.A. (http://www.rcsb.org/search?q=citation.rcsb_authors:Goldsmith,%20J.A.), Hsieh, C.L. (http://www.rcsb.org/search?q=citation.rcsb_authors:Hsieh,%20C.L.), Abiona, O. (http://www.rcsb.org/search?q=citation.rcsb_authors:Abiona,%20O.), Graham, B.S. (http://www.rcsb.org/search?q=citation.rcsb_authors:Graham,%20B.S.), McLellan, J.S. (http://www.rcsb.org/search?q=citation.rcsb_authors:McLellan,%20J.S.) (2020) Science 367 : 1260-1263 Blue: N-Terminal Domain (NTD) Green: Receptor Binding Domain (RBD) Tan: Remainder of S1 Cyan: Fusion Peptide Yellow: Heptad Repeat 1 Orange: Central Helix Purple: Connector Domain Red: Remainder of S2 See also 3dpx-012877 (https://3dprint.nih.gov/discover/3dpx-012877) for a related structure from SARS-CoV with all RBD down in the inactive conformation.