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Description
Ceftobiprole is a fifth-generation cephalosporin antibiotic having (E)-[(3'R)-2-oxo[1,3'-bipyrrolidin]-3-ylidene]methyl and [(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino side groups located at positions 3 and 7 respectively; developed for the treatment of hospital-acquired pneumonia (HAP, excluding ventilator-associated pneumonia, VAP) and community-acquired pneumonia (CAP). It has a role as an antimicrobial agent. It is a cephalosporin and a member of thiadiazoles.
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- Source creator
- Kzoghebi
- Source license
- CC-BY
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#nih-3d
#small molecules
#ceftobiprole
#209467-52-7
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#ceftobiprole [usan:inn]
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#bal9141
#bal 9141
#(6r,7r)-7-[[(2z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-hydroxyiminoacetyl]amino]-8-oxo-3-[(e)-[2-oxo-1-[(3r)-pyrrolidin-3-yl]pyrrolidin-3-ylidene]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#bal-9141
#ceftobiprole [mi]
#ceftobiprole [inn]
#ro-63-9141/000
#ceftobiprole [usan]
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#ceftobiprole, antibiotic for culture media use only
#(6r,7r)-7-((2z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)-acetamido)-8-oxo-3-((e)((3'r)-2-oxo-(1,3'-bipyrrolidin)-3-ylidene)-methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid antibiotic
#(6r,7r)-7-((2z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetamido)-8-oxo-3-((e)((3'r)-2-oxo-(1,3'-bipyrrolidin)-3-ylidene)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
#(6r,7r)-7-{[(2z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-8-oxo-3-{(e)-[(3'r)-2-oxo[1,3'-bipyrrolidin]-3-ylidene]methyl}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2z)-(5-amino-1,2,4-thiadiazol-3-yl)(hydroxyimino)acetyl)amino)-8-oxo-3-((e)-((3'r)-2-
#5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2z)-(5-amino-1,2,4-thiadiazol-3-yl)(hydroxyimino)acetyl)amino)-8-oxo-3-((e)-((3'r)-2-oxo(1,3'-bipyrrolidin)-3-ylidene)methyl)-, (6r,7r)-
#7-{[(2z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-3-{(e)-[(3'r)-2-oxo[1,3'-bipyrrolidin]-3-ylidene]methyl}-3,4-didehydrocepham-4-carboxylic acid
#(6r,7r)-7-(((2z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-hydroxyiminoacetyl)amino)-8-oxo-3-((e)-(2-oxo-1-((3r)-pyrrolidin-3-yl)pyrrolidin-3-ylidene)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
#refchem:574985
#dtxcid40820709
#(6r,7r)-7-((2z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(n-hydroxyimino)acetamido)-8-oxo-3-(((3e,3'r)-2-oxo-(1,3'-bipyrrolidin)-3-ylidene)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
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