Cephalothin
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Description

Cefalotin is a semisynthetic, first-generation cephalosporin antibiotic with acetoxymethyl and (2-thienylacetyl)nitrilo moieties at positions 3 and 7, respectively, of the core structure. Administered parenterally during surgery and to treat a wide spectrum of blood infections. It has a role as an antimicrobial agent and an antibacterial drug. It is a cephalosporin, a member of thiophenes, a carboxylic acid, an azabicycloalkene, a semisynthetic derivative and a beta-lactam antibiotic allergen. It is a conjugate acid of a cefalotin(1-).

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Source creator
Kzoghebi
Source license
CC-BY
Archived copies are shared under the license shown.
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#nih-3d
#small molecules
#cephalothin
#cefalotin
#153-61-7
#cephalotin
#cefalothin
#cephalothinum
#cefalotina
#cefalotine
#cefalotinum
#cemastin
#(6r,7r)-3-(acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#7-(2-thienylacetamido)cephalosporanic acid
#coaxin
#keflin
#cefalotine [inn-french]
#cefalotinum [inn-latin]
#cefalotina [inn-spanish]
#averon-1
#cephalotin acid
#7-(thiophene-2-acetamido)cephalosporin
#(6r,7r)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#3-acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid
#cefalotin [inn]
#(6r,7r)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#chebi:124991
#mls001048966
#7-(2'-thienylacetamido)cephalosporanic acid
#r72lw146e6
#5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-8-oxo-7-((2-thienylacetyl)amino)-, (6r-trans)-
#ncgc00159332-02
#smr000386987
#dsstox_cid_2783
#dsstox_rid_76728
#dsstox_gsid_22783
#cefalotin (ban)
#7-(thiophene-2-acetamido)cephalosporanic acid
#(6r,7r)-3-(acetoxymethyl)-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#cas-153-61-7
#7-(2-(2-thienyl)acetylamido)cephalosporanic acid
#hsdb 3024
#cefalotina fabra (tn)
#58-71-9
#einecs 205-815-7
#brn 0945586
#unii-r72lw146e6
#6r-trans-3-((acetyloxy)methyl)-8-oxo-7-((2-thienylacetyl)amino)-5-thia-1-azabicyclo(4.2.0)-oct-2-ene-2-carboxylic acid
#4kox
#5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-8-oxo-7-((2-thienylacetyl)amino)-, (6r,7r)-
#5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-, (6r,7r)-
#3-(acetoxymethyl)-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
#3-(hydroxymethyl)-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid acetate
#spectrum_000110
#cephalothin [mi]
#prestwick0_000719
#prestwick1_000719
#prestwick2_000719
#prestwick3_000719
#spectrum2_000121
#spectrum3_000332
#spectrum4_000269
#spectrum5_000669
#cephalothin [hsdb]
#chembl617
#epitope id:116207
#cephalothin [vandf]
#cefalotin [who-dd]
#cid_6024
#schembl2990
#lopac0_000283
#bspbio_000937
#bspbio_001963
#kbiogr_000738
#kbioss_000550
#3-acetoxymethyl-8-oxo-7-(2-thiophen-2-yl-acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-(2-(2-thienyl)acetamido)-, acetate (ester)
#divk1c_000097
#spbio_000162
#spbio_002858
#bpbio1_001031
#gtpl8798
#cephalothin [green book]
#dtxsid4022783
#schembl20477170
#bdbm82898
#hy-b1275a
#kbio1_000097
#kbio2_000550
#kbio2_003118
#kbio2_005686
#kbio3_001183
#ninds_000097
#hms2267p23
#zinc3830507
#tox21_111579
#mfcd00242614
#s5294
#akos015920120
#tox21_111579_1
#ccg-268605
#cs-w008776
#db00456
#gs-3577
#sdccgsbi-0050271.p005
#7beta-(thiophen-2-ylacetamido)-3-acetoxymethyl-3,4-didehydrocepham-4-carboxylic acid
#idi1_000097
#ncgc00023699-09
#(6r,7r)-3-(acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid
#(6r,7r)-3-[(acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#sbi-0050271.p004
#7-(2-thienylacetamido) cephalosporanic acid
#7-(2-thienylacetamido)-cephalosporanic acid
#c-2484
#c07761
#d07635
#153c617
#a809447
#cephalothin, antibiotic for culture media use only
#sr-01000003118
#q2736126
#sr-01000003118-3
#brd-k28210218-236-05-7
#z1741977144
#cephalothin 7-(2-thienylacetamido)cephalosporanic acid
#3-acetoxymethyl-7beta-(2-thienylacetamido) ceph-3-em-4-carboxylic acid
#3-acetoxymethyl-7beta-(2-thienylacetamido)-3-cephem-4-carboxylic acid
#3-acetoxymethyl-7beta-(2-thienylacetamido)ceph-3-em-4-carboxylic acid
#(6r,7r)-3-(acetoxymethyl)-8-keto-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#(6r,7r)-3-(acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#(6r,7r)-3-(acetyloxymethyl)-8-oxidanylidene-7-(2-thiophen-2-ylethanoylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#(6r,7r)-3-(acetyloxymethyl)-8-oxo-7-[(1-oxo-2-thiophen-2-ylethyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#(6r,7r)-3-[(acetyloxy)methyl]-8-oxo-7-[(thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
#(+-)-cephalothin
#51098-29-4
#en300-267043
#dtxcid202783
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d

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Cephalothin

From NIH 3D
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Category

learning

License

CC-BY

Published

9/22/2026

Availability

free on NIH 3D