Oleuropein
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Description

Oleuropein is a secoiridoid glycoside that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the anomeric hydroxy group at position 2 has been converted into its beta-D-glucoside and the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2S,3E,4S stereoisomer). The most important phenolic compound present in olive cultivars. It has a role as an antioxidant, an antineoplastic agent, an antihypertensive agent, a radical scavenger, a nutraceutical, an anti-inflammatory agent, an apoptosis inducer, a NF-kappaB inhibitor and a plant metabolite. It is a beta-D-glucoside, a methyl ester, a member of pyrans, a member of catechols, a secoiridoid glycoside and a diester.

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Source creator
Colin Lemire
Source license
CC-BY
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#nih-3d
#small molecules
#oleuropein
#32619-42-4
#unii-2o4553545l
#einecs 251-129-6
#2o4553545l
#2-(3,4-dihydroxyphenyl)ethyl (2s-(2alpha,3e,4beta))-3-ethylidene-2-(beta-d-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2h-pyran-4-acetate
#oleoeuropein
#c20h24o7
#c25h32o13
#methyl (2s,3e,4s)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2h-pyran-5-carboxylate
#methyl (4s,5e,6s)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4h-pyran-3-carboxylate
#oleoeuropeine
#2h-pyran-4-acetic acid, 3-ethylidene-2-(.beta.-d-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(3,4-dihydroxyphenyl)ethyl ester, (2s,3e,4s)-
#oleuroperin
#oleuropein [mi]
#oleuropein [inci]
#oleuropein [vandf]
#oleuropein, >=98.0%
#oleuropein [usp-rs]
#oleuropein [who-dd]
#oleuropein, analytical standard
#chebi:7747
#megxp0_000369
#schembl4306969
#chembl1911053
#oleuropein, >=80% (hplc)
#acon1_000443
#gtpl11027
#dtxsid60905103
#hy-n0292
#zinc4098348
#mfcd16879008
#akos015900702
#ccg-269961
#ncgc00169074-01
#ncgc00169074-02
#as-56230
#cs-0008800
#o0420
#s7867
#a12095
#q402625
#oleuropein, primary pharmaceutical reference standard
#brd-k08037284-001-01-4
#oleuropein, european pharmacopoeia (ep) reference standard
#oleuropein, united states pharmacopeia (usp) reference standard
#(4s)-5,6-dihydro-5-ethylidene-3-(methoxycarbonyl)-6alpha-(beta-d-glucopyranosyloxy)-4h-pyran-4beta-acetic acid 2-(3,4-dihydroxyphenyl)ethyl ester
#[2s-(2alpha,3e,4beta)]-3-ethylidene-2-(beta-d-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2h-pyran-4-acetic acid 2-(3,4-dihydroxyphenyl)ethyl ester
#2h-pyran-4-acetic acid, 3-ethylidene-2-(.beta.-d-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(3,4-dihydroxyphenyl)ethyl ester, (2s-(2.alpha.,3e,4.beta.))-
#2h-pyran-4-acetic acid, 5-carboxy-3-ethylidene-2-(.beta.-d-glucosyloxy)-3,4-dihydro-, 3,4-dihydroxyphenethyl 5-methyl ester
#methyl (2s,3e,4s)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-(beta-d-glucopyranosyloxy)-3,4-dihydro-2h-pyran-5-carboxylate
#methyl (2s,4s,e)-4-(2-(3,4-dihydroxyphenethoxy)-2-oxoethyl)-3-ethylidene-2-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)oxy)-3,4-dihydro-2h-pyran-5-carboxylate
#methyl (4s,5e,6s)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxo-ethyl]-5-ethylidene-6-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4h-pyran-3-carboxylate
#methyl(4s,5e,6s)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4h-pyran-3-carboxylate
#methyl (4s,5e,6s)-4-(2-(2-(3,4-dihydroxyphenyl)ethoxy)-2-oxoethyl)-5-ethylidene-6-((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy-4h-pyran-3-carboxylate
#refchem:168112
#dtxcid401334206
#methyl (4s,5z,6r)-4-(2-(2-(3,4-dihydroxyphenyl)ethoxy)-2-oxo-ethyl)-5-ethylidene-6-((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl)oxy-4h-pyran-3-carboxylate
#251-129-6
#oleuropein, 75%
#oleuropein, >95%
#oleuropeine
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d

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Oleuropein

From NIH 3D
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Category

learning

License

CC-BY

Published

9/23/2026

Availability

free on NIH 3D