Click to view full size
Description
Vemurafenib is a pyrrolopyridine that is 1H-pyrrolo[2,3-b]pyridine which is substituted at position 5 by a p-chlorophenyl group and at positions 3 by a 3-amino-2,6-difluorobenzoyl group, the amino group of which has undergone formal condensation with propane-1-sulfonic acid to give the corresponding sulfonamide. An inhibitor of BRAF and other kinases. It has a role as an antineoplastic agent and a B-Raf inhibitor. It is a sulfonamide, a difluorobenzene, a pyrrolopyridine, an aromatic ketone and a member of monochlorobenzenes.
From NIH 3D
Model source and downloads
This page preserves searchable metadata and attribution. Use NIH 3D for the current files and source details.
- Source creator
- Kzoghebi
- Source license
- CC-BY
Archived copies are shared under the license shown.
View/download on NIH 3DTags
#nih-3d
#small molecules
#vemurafenib
#918504-65-1
#plx4032
#zelboraf
#1029872-54-5
#plx-4032
#rg7204
#n-(3-(5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
#plx 4032
#vemurafenib (plx4032, rg7204)
#rg 7204
#n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide
#ro 5185426
#vemurafenib (plx4032)
#ro5185426
#rg-7204
#207smy3fqt
#ro-5185426
#chebi:63637
#mfcd18074504
#nsc761431
#n-(3-((5-(4-chlorophenyl)-1h-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4- difluorophenyl)propane-1-sulfonamide
#vemurafenib;plx-4032
#ro-51-85426
#1-propanesulfonamide, n-(3-((5-(4-chlorophenyl)-1h-pyrrolo(2,3-b)pyridin-3- yl)carbonyl)-2,4-difluorophenyl)-
#1-propanesulfonamide, n-[3-[[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-
#n-[3-[[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide
#n-[3-[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]propane-1-sulfonamide
#n-{3-[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide
#zelboraf (tn)
#1-propanesulfonamide, n-(3-((5-(4-chlorophenyl)-1h-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4-difluorophenyl)-
#1415041-85-8
#n-(3-((5-(4-chlorophenyl)-1h-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4-difluorophenyl)-1-propanesulfonamide
#vemurafenib [usan]
#vemurafenib [usan:inn]
#unii-207smy3fqt
#vemurafenibum
#ro 51-85426
#hsdb 8143
#n-(3-{(5-(4-chlorophenyl)-1h-pyrrolo(2,3-b)pyridin-3-yl)carbonyl}-2,4- difluorophenyl)propane-1-sulfonamide
#3og7
#vemurafenib [mi]
#vemurafenib; plx4032
#vemurafenib [inn]
#vemurafenib [jan]
#plx4032 - vemurafenib
#vemurafenib [vandf]
#vemurafenib [mart.]
#vemurafenib [who-dd]
#schembl298931
#vemurafenib (jan/usan/inn)
#gtpl5893
#chembl1229517
#dtxsid50238710
#ex-a053
#vemurafenib [orange book]
#hms3265m03
#hms3265m04
#hms3265n03
#hms3265n04
#hms3654p09
#hms3748g15
#bcp25783
#ex-a1335
#bdbm50396483
#nsc800964
#s1267
#zinc52509366
#akos007930804
#am81259
#ccg-264883
#cs-0216
#db08881
#me-0096
#nsc-761431
#nsc-800964
#pb11741
#ncgc00250399-01
#ncgc00250399-05
#ncgc00250399-08
#vemurafenib, rg7204, ro5185426
#ac-25010
#hy-12057
#n-[3-[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl]propane-1-sulfonamide
#sy067868
#ft-0660388
#ft-0675792
#ft-0689782
#sw218095-2
#a25476
#a25742
#d09996
#r-7204
#ab01273970-01
#ab01273970_03
#q423111
#sr-01000941568
#carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide
#j-522975
#j-690009
#sr-01000941568-1
#brd-k56343971-001-02-3
#brd-k56343971-001-05-6
#plx4032,vemurafenib, rg7204, ro5185426, zelboraf
#n-{3-[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridine-3-
#[(2s,5r)-2,5-dimethyl-4-[(tetrahydro-2h-pyran-4-yl)methyl]-1-piperazinyl][3-[(5-fluoro-2-methyl-4-pyrimidinyl)amino]-4,6-dihydro-6,6 -dimethylpyrrolo[3,4-c]pyrazol-5(1h)-yl]methanone
#n-(3-(5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)-propane-1-sulfonamide
#propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide
#en300-23265091
#n-(3-((5-(4-chlorophenyl)-1h-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
#refchem:57849
#dtxcid00161201
#l01xe15
#braf(v600e) kinase inhibitor ro5185426
#braf (v600e) kinase inhibitor ro5185426
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d
Makes
See how others have printed this model