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Description
Tofacitinib is a pyrrolopyrimidine that is pyrrolo[2,3-d]pyrimidine substituted at position 4 by an N-methyl,N-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely active rheumatoid arthritis. It has a role as an antirheumatic drug and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a nitrile, a pyrrolopyrimidine, a N-acylpiperidine and a tertiary amino compound.
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- Source creator
- Kzoghebi
- Source license
- CC-BY
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#nih-3d
#small molecules
#tofacitinib
#tasocitinib
#477600-75-2
#3-((3r,4r)-4-methyl-3-(methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
#cp-690550
#cp 690550
#racemic-tofacitinib
#1259404-17-5
#tofacitinibum
#unii-87la6fu830
#rac-tofacitinib
#cp-690,550
#tofacitinib (cp-690550,tasocitinib)
#3-((3r,4r)-rel-4-methyl-3-(methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
#tofacitinib [usan]
#cp-690 free base
#cp690550
#3-{(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile
#chembl221959
#chebi:71200
#87la6fu830
#cp-690550 free base
#cp-690,550 free base
#477600-75-2 (free base)
#tofacitinib (usan)
#cp690,550
#cp-690-550
#3-((3r,4r)-4-methyl-3-(methyl(7h-pyrrolo(2,3-d)pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
#mfcd11035919
#3-[(3r*,4r*)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile
#3-[(3r,4r)-4-methyl-3-[methyl({7h-pyrrolo[2,3-d]pyrimidin-4-yl})amino]piperidin-1-yl]-3-oxopropanenitrile
#3-{(3r,4r)-4-methyl-3-[methyl-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile
#3-piperidinamine, 1-(cyanoacetyl)-4-methyl-n-methyl-n-1h-pyrrolo(2,3-d)pyrimidin-4-yl-, (3r,4r)-
#tofacitinib [usan:inn]
#3eyg
#3fup
#3lxk
#4oti
#3-[(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile
#mi1
#tofacitinib [mi]
#(+)-tofacitinib
#tofacitinib [inn]
#tofacitinib [vandf]
#tofacitinib [who-dd]
#1-piperidinepropanenitrile, 4-methyl-3-(methyl-7h-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-, (3r,4r)-
#schembl322753
#tofacitinib (cp-690550)
#gtpl5677
#hsdb 8311
#amy3992
#dtxsid90197271
#ex-a205
#bcpp000274
#zinc3818808
#bdbm50193995
#nsc782351
#nsc800953
#s2789
#akos005145814
#akos005258733
#ac-8193
#bcp9000550
#ccg-264998
#cs-0050
#db08895
#gs-6106
#nsc-782351
#nsc-800953
#ncgc00229511-02
#ncgc00229511-04
#ncgc00229511-10
#ncgc00244463-01
#tofacitinib (cp-690550, tasocitinib)
#hy-40354
#cp- 690 550
#d09970
#ab01565786_02
#600m752
#ar-270/43507983
#j-524314
#q3530324
#brd-k31283835-001-01-9
#brd-k31283835-048-04-4
#3-((3r,4r)-4-methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yi)amino)piperidin-1-yl-3-oxopropaneni
#(3r,4r)-3-{4-methyl-3-[methyl-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile
#(3r,4r)-4-methyl-3-(methyl-7h-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidine propanenitrile
#1-piperidinepropanenitrile, 4-methyl-3-(methyl-7h-pyrrolo(2,3-d)pyrimidin-4-ylamino)-.beta.-oxo-, (3r,4r)-
#3-[(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-1-piperidyl]-3-oxo-propanenitrile
#3-{(3r,4r)-4-methyl-3-[methyl-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]piperidin-1-yl}-3-oxo-propionitrile
#3-{(3r,4r)-4-methyl-3-[methyl-(7h-pyrrolo[2,3-d]pyrimidin4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile
#3-{4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-1-piperidinyl}-3-oxopropanenitrile
#tofacitinib;3-((3r,4r)-4-methyl-3-(methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
#en300-1718468
#a7301
#cp-690
#3-((3r,4r)-4-methyl-3-(methyl((7h-pyrrolo(2,3-d)pyrimidin-4-yl))amino)piperidin-1-yl)-3-oxopropanenitrile
#refchem:6313
#jak inhibitors: tofacitinib
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d
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