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Regorafenib

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Description

Regorafenib is a pyridinecarboxamide obtained by condensation of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]pyridine-2-carboxylic acid with methylamine. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor and a hepatotoxic agent. It is a member of phenylureas, a pyridinecarboxamide, an aromatic ether, a member of monochlorobenzenes, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes.

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Source creator: Kzoghebi
Source license: CC-BY

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Tags

#small molecules

#4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-n-methylpicolinamide

#regorafenib (bay 73-4506)

#unii-24t2a1doyb

#4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide

#regorafenib-13c-d3

#4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-n-methylpyridine-2-carboxamide

#4-(4-(((4-chloro-3-(trifluoromethyl)phenyl)carbamoyl)amino)-3-fluorophenoxy)-n-methylpyridine-2-carboxamide

#regorafenib [inn]

#regorafenib [usan:inn]

#fluoro-sorafenib

#4-(4-(((4-chloro-3-(trifluoromethyl)phenyl)carbamoyl}amino)-3-fluorophenoxy)-n-methylpyridine-2-carboxamide

#regorafenib [mi]

#regorafenib (usan/inn)

#regorafenib [vandf]

#regorafenib anhydrous

#regorafenib [who-dd]

#regorafenib crystalline form i

#regorafenib,bay 73-4506

#dtxsid60226441

#regorafenib - bay 73-4506

#ncgc00263138-01

#ncgc00263138-13

#ncgc00263138-19

#2-pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-n-methyl-

#cas:835621-07-3;regorafenib hydrochloride

#regorafenib (bay73-4506,fluoro-sorafenib)

#sr-01000941571

#sr-01000941571-1

#brd-k16730910-001-02-4

#2-pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-n-methyl-

#4-[4-({[4-chloro-3-(trifluoromethy)phenyl]carbamoyl}amino)-3-fluorophenoxy]-1-methylpyridine-2-carboxamide

#4{4-[3-(4-chloro-3-trifluoromethylphenyl)-ureido]-3-fluorophenoxy}-pyridine-2-carboxylic acid methylamide

#regorafenib;1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea

#bay-734506 monohydrate

#bay 73-4506 monohydrate

#bay-73-4506 monohydrate

#4-(4-((4-chloro-3-(trifluoromethyl)phenyl)carbamoylamino)-3-fluorophenoxy)-n-methylpyridine-2-carboxamide

#dtxcid60148932

#2-pyridinecarboxamide, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)-3-fluorophenoxy)-n-methyl-, hydrate (1:1)

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Regorafenib

From NIH 3D

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License

CC-BY

Published

8/30/2026

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free on NIH 3D