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Description
Pralatrexate is a pteridine that is the N-4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl derivative of L-glutamic acid. Used for treatment of Peripheral T-Cell Lymphoma, an aggressive form of non-Hodgkins lymphoma. It has a role as an antimetabolite, an antineoplastic agent and an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. It is a N-acyl-L-glutamic acid, a member of pteridines and a terminal acetylenic compound.
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- Source creator
- Kzoghebi
- Source license
- CC-BY
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#nih-3d
#small molecules
#pralatrexate
#146464-95-1
#folotyn
#10-propargyl-10-deazaaminopterin
#hsdb 7786
#folotyn (tn)
#pralatrexate(folotyn)
#pdx
#n-(4-(1-((2,4-diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-l-glutamic acid
#(2s)-2-(4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzamido)pentanedioic acid
#chebi:71223
#nsc-754230
#(2s)-2-((4-((1rs)-1-((2,4-diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid
#a8q8i19q20
#146464-95-1 (racemic)
#l-glutamic acid, n-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-
#ncgc00242596-01
#(2s)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid
#(2s)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid
#n-{4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}-l-glutamic acid
#l-glutamic acid, n-(4-(1-((2,4-diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-
#n -(4-{1-[(2,4-diaminopteridin-6-yl)methyl]but-3-yn-1-yl}benzoyl)-l-glutamic acid
#pralatrexate [usan]
#pralatrexate [usan:inn]
#pralatrexato
#pralatrexatum
#pralatrexat
#unii-a8q8i19q20
#pralatrexate [mi]
#pralatrexate [inn]
#pralatrexate [jan]
#pralatrexate [hsdb]
#dsstox_cid_28504
#dsstox_rid_82776
#pralatrexate [vandf]
#dsstox_gsid_48578
#schembl21633
#pralatrexate [mart.]
#pralatrexate [who-dd]
#gtpl6840
#pralatrexate (jan/usan/inn)
#chembl1201746
#dtxsid3048578
#schembl15075302
#bcpp000101
#pralatrexate [orange book]
#ex-a2142
#tox21_112906
#bdbm50457437
#mfcd00920897
#nsc754230
#s1497
#akos015966891
#am84423
#ccg-269517
#cs-0504
#db06813
#nsc 754230
#s11194
#10-propargyl-10-deazaaminopterin, 95%
#ncgc00386226-01
#ac-28388
#bs-15438
#hy-10446
#cas-146464-95-1
#p2645
#sw220187-1
#d05589
#ab00443251-02
#ab00443251_04
#464p951
#a884505
#q637059
#sr-01000941578
#j-008227
#sr-01000941578-1
#n-(4-(1-((2,4-diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-l-glutamic acid;pralatrexate
#(2s)-2-[[4-[(1rs)-1-[(2,4-diaminopteridin-6-yl)methyl]but-3-ynyl]benzoyl]amino]pentanedioic acid
#en300-26509071
#(2s)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid
#dtxcid3028504
#(2s)-2-((4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)amino)pentanedioic acid
#n-(4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-l-glutamic acid
#refchem:57047
#l01ba05
#n-(4-(1-((2,4-diaminopteridin-6-yl)methyl)but-3-yn-1-yl)benzoyl)-l-glutamic acid
#(2s)-2-((4-((1rs)-1-((2, 4-diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d
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