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Description
Palbociclib is a member of the class of pyridopyrimidines that is 2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7-one bearing additional methyl, acetyl and cyclopentyl substituents at positions 5, 6 and 8 respectively. It is used in combination with letrozole for the treatment of metastatic breast cancer. It has a role as an antineoplastic agent and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a member of cyclopentanes, a member of piperidines, an aminopyridine, a pyridopyrimidine, a secondary amino compound, a tertiary amino compound and an aromatic ketone.
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- Source creator
- Kzoghebi
- Source license
- CC-BY
Archived copies are shared under the license shown.
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#nih-3d
#small molecules
#palbociclib
#571190-30-2
#pd0332991
#pd-0332991
#ibrance
#pd 0332991
#unii-g9zf61le7g
#palbociclib(pd0332991)
#pd-332991
#6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8h)-one
#palbociclib free base
#571190-30-2 (free base)
#mfcd11840850
#6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7(8h)-one
#6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8h-pyrido[2,3-d]pyrimidin-7-one
#g9zf61le7g
#pd 332991
#6-acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-ylpyridin-2-ylamino)-8h-pyrido(2,3-d)pyrimidin-7-one
#chebi:85993
#6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one
#lqq
#2euf
#6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one
#pyrido(2,3-d)pyrimidin-7(8h)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(1-piperazinyl)-2-pyridinyl)amino)-
#palbociclib [usan]
#571190-30-2 pound not827022-32-2
#palbociclib [usan:inn]
#[d8]-palbociclib
#6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-8h-pyrido(2,3-d)pyrimidin-7-one
#ibrance (tn)
#palbociclib- bio-x
#kinome_3823
#kinome_3824
#palbociclib [mi]
#6-acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8h-pyrido[2,3-d]pyrimidin-7-one hydrochloride
#palbociclib [inn]
#palbociclib [jan]
#palbociclib (jan/usan)
#palbociclib [who-dd]
#schembl462630
#bdbm6309
#chembl189963
#gtpl7380
#pd 0332991 (palbociclib)
#dtxsid40972590
#ex-a408
#palbociclib [orange book]
#2euf; pd 0332991
#otava-bb 1115529
#bcpp000125
#hms3265m09
#hms3265m10
#hms3265n09
#hms3265n10
#hms3744g13
#amy14886
#bcp09274
#bcp18381
#zinc3938686
#nsc758247
#nsc772256
#nsc800815
#s4482
#akos022205241
#bcp9001058
#db09073
#nsc-758247
#nsc-772256
#nsc-800815
#sb40426
#pyrido-[2,3-d]-pyrimidin-7-one 43
#ncgc00263129-01
#ncgc00263129-08
#ncgc00263129-21
#ncgc00263129-22
#ac-25485
#as-17016
#bp166224
#hy-50767
#sy026143
#ft-0697059
#a14427
#d10372
#190p302
#pd 0332991,pd0332991
#pd-0332991, pd0332991
#brd-k51313569-001-01-1
#p-0332991
#q15269707
#6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino(pyrido(2,3-d)pyrimidin-7(8h)-one
#6-acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8h-pyrido[2,3-d]pyrimidin-7-one
#6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[6,5-d]pyrimidin-7-one
#6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridyl]amino]pyrido[2,3-d]pyrimidin-7(8h)-one
#6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)-pyridin-2-yl]amino]-8h-pyrido[2,3-d]pyrimidin-7-one
#8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7h,8h-pyrido[2,3-d]pyrimidin-7-one
#6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7h,8h-pyrido[2,3-d]pyrimidin-7-one
#en300-18531248
#z2216894329
#a8153
#pyrido[2,3-d]pyrimidin-7(8h)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-
#palbociclibum
#6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido(2,3-d)pyrimidin-7(8h)-one
#6-acetyl-8-cyclopentyl-5-methyl-2-((5-piperazin-1-ylpyridin-2-yl)amino)pyrido(6,5-d)pyrimidin-7-one
#refchem:6097
#dtxcid80207212
#l01xe33
#pd 991
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d
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