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Description
Crizotinib is a 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that has R configuration at the chiral centre. The active enantiomer, it acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC). It has a role as an antineoplastic agent, a biomarker and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is an enantiomer of an ent-crizotinib.
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- Source creator
- Kzoghebi
- Source license
- CC-BY
Archived copies are shared under the license shown.
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#nih-3d
#small molecules
#crizotinib
#877399-52-5
#xalkori
#(r)-crizotinib
#pf-2341066
#pf-02341066
#pf 2341066
#crizotinibum
#crizotinib (pf-02341066)
#3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1h-pyrazol-4-yl]-2-pyridinamine
#(r)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1h-pyrazol-4-yl)pyridin-2-amine
#pf 02341066
#pf2341066
#chembl601719
#crizotinib (pf-2341066)
#chebi:64310
#877399-52-5 (free base)
#53ah36668s
#nsc-756645
#3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]pyridin-2-amine
#2-pyridinamine, 3-((1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(4-piperidinyl)-1h-pyrazol-4-yl)-
#3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amine
#3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
#3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1h-pyrazol-4-yl]pyridin-2-amine
#(r)-3-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)-pyridin-2-ylamine
#xalkori (tn)
#crizotinib [usan]
#crizotinib [usan:inn]
#unii-53ah36668s
#3-((1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1h-pyrazol-4-yl)pyridin-2-amine
#vgh
#crizotinib- bio-x
#crizotinib [mi]
#crizotinib [inn]
#crizotinib [jan]
#pf02341066
#crizotinib [vandf]
#crizotinib [mart.]
#crizotinib [who-dd]
#schembl93829
#pf-2341066,crizotinib
#crizotinib (jan/usan/inn)
#gtpl4903
#crizotinib [orange book]
#crizotinib, >=98% (hplc)
#pf-2341066 - crizotinib
#ex-a096
#bcpp000116
#dtxsid701009329
#amy10313
#bdbm50306682
#mfcd12407409
#nsc749005
#nsc749769
#nsc800080
#zinc35902489
#akos015901233
#akos015995207
#ccg-264803
#db08865
#gs-6178
#nsc 756645
#nsc-749005
#nsc-749769
#nsc-800080
#ncgc00250400-01
#ncgc00250400-02
#ncgc00250400-09
#ncgc00250400-12
#bc164334
#hy-50878
#bb 0261738
#sw202555-3
#d09731
#399p525
#j-510370
#q5186964
#brd-k78431006-001-01-1
#brd-k78431006-001-03-7
#877399-52-5, 877399-53-6 (acetate)
#3-(2,6-dichloro-3-fluorobenzyloxy)-5-(1-(piperidin-4-yl)-1h-pyrazol-4-yl)pyridin-2-amine
#(r)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1h-pyrazol-4-yl)pyridin-2-am ine
#3-(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy-5-1-(4-piperidinyl)-1h-pyrazol-4-yl-2-pyridinamine
#3-[(r)-1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)-pyridin-2-ylamine
#3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1h-pyrazol-4-yl)pyridin-2-amine
#z2065417924
#2-pyridinamine, 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1h-pyrazol-4-yl]-
#refchem:57397
#l01xe16
#dtxcid601436157
#met tyrosine kinase inhibitor pf-02341066
#638-814-9
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d
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