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Description
Camptothecin is a pyranoindolizinoquinoline that is pyrano[3',4':6,7]indolizino[1,2-b]quinoline which is substituted by oxo groups at positions 3 and 14, and by an ethyl group and a hydroxy group at position 4 (the S enantiomer). It has a role as an antineoplastic agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, a genotoxin and a plant metabolite. It is a delta-lactone, a quinoline alkaloid, a tertiary alcohol and a pyranoindolizinoquinoline.
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- Source creator
- Kzoghebi
- Source license
- CC-BY
Archived copies are shared under the license shown.
View/download on NIH 3DTags
#nih-3d
#small molecules
#(+)-camptothecin
#4-ethyl-4-hydroxy-1h-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione
#251316-95-7
#4-ethyl-4-hydroxy-1,12-dihydro-4h-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione
#camptothecin
#camptothecine
#7689-03-4
#(s)-(+)-camptothecin
#campathecin
#(+)-camptothecine
#d-camptothecin
#20(s)-camptothecine
#21,22-secocamptothecin-21-oic acid lactone
#nsc94600
#camptothecine (s,+)
#chembl65
#(4s)-4-ethyl-4-hydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione
#nsc-94600
#(s)-4-ethyl-4-hydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione
#mls000766223
#xt3z54z28a
#chebi:27656
#mfcd00081076
#(19s)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
#(s)-camptothecin
#(19s)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
#1h-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione, 4-ethyl-4-hydroxy-, (4s)-
#1h-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione, 4-ethyl-4-hydroxy-, (s)-
#1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione, 4-ethyl-4-hydroxy-, (4s)-
#20(s)-camptothecin
#sr-01000075798
#sr-01000597379
#d-camptothecine
#(s)-camptothecine
#camptothecin,(s)
#( )-camptothecin
#(4s)-4-ethyl-4-hydroxy-1h-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione
#(s)-4-ethyl-4-hydroxy-1h-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione
#(s)-4-ethyl-4-hydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4h,12h)-dione
#1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione, 4-ethyl-4-hydroxy-, (s)-
#prestwick_102
#(+)-camptothecin;
#camptothecine (8ci)
#spectrum_000299
#tocris-1100
#specplus_000712
#prestwick0_000200
#prestwick1_000200
#prestwick2_000200
#prestwick3_000200
#spectrum2_000903
#spectrum3_001203
#spectrum4_000738
#spectrum5_001126
#camptothecin [mi]
#lopac-c-9911
#schembl6038
#unii-xt3z54z28a
#lopac0_000341
#bspbio_000159
#bspbio_002586
#kbiogr_001036
#kbioss_000779
#kbioss_002283
#cid_24360
#camptothecin [who-dd]
#divk1c_000826
#divk1c_006808
#spectrum1502232
#spbio_000746
#spbio_002080
#bpbio1_000175
#ccris 8162
#dtxsid0030956
#hms502j08
#kbio1_000826
#kbio1_001752
#kbio2_000779
#kbio2_003347
#kbio2_005915
#kbio3_002086
#ninds_000826
#bio1_000400
#bio1_000889
#bio1_001378
#hms1568h21
#hms1921n08
#hms2089f08
#hms2095h21
#hms3261e03
#hms3414j17
#hms3654d13
#hms3678j15
#hms3712h21
#zinc105309
#act02668
#bcp02857
#tox21_500341
#ac-202
#bbl033963
#bdbm50008923
#ccg-40255
#gr-301
#nsc 94600
#s1288
#stk801886
#akos004119861
#cs-1049
#db04690
#ks-5235
#lp00341
#sdccgmls-0066688.p001
#sdccgsbi-0050329.p003
#brn 0631069
#cas-2114454
#idi1_000826
#ncgc00015290-01
#ncgc00016994-01
#ncgc00016994-02
#ncgc00016994-03
#ncgc00016994-04
#ncgc00016994-05
#ncgc00016994-06
#ncgc00016994-07
#ncgc00016994-08
#ncgc00016994-09
#ncgc00016994-10
#ncgc00016994-11
#ncgc00016994-12
#ncgc00016994-16
#ncgc00016994-29
#ncgc00024997-01
#ncgc00024997-02
#ncgc00024997-03
#ncgc00024997-04
#ncgc00024997-05
#ncgc00024997-06
#ncgc00178592-01
#ncgc00178592-02
#ncgc00261026-01
#hy-16560
#nci60_042105
#smr000445686
#sy010324
#ai3-62475
#eu-0100341
#sw196414-3
#c 9911
#c01897
#m01564
#ab00052452-08
#ab00052452-09
#ab00052452_10
#(s)-(+)-camptothecin, >=90% (hplc), powder
#689c034
#a838882
#q419964
#q-200785
#sr-01000075798-1
#sr-01000075798-4
#sr-01000597379-1
#sr-01000597379-3
#brd-k37890730-001-09-4
#brd-k37890730-001-10-2
#(s)-4-ethyl-4-hydroxy-1,12-dihydro-4h-2-oxa-6,12a-diaza-dibenzo[b,h]florene-3,13-dione
#(s)-4-ethyl-4-hydroxy-1,12-dihydro-4h-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione
#4-ethyl-4-hydroxy-1h-pyrano-[3[,4[:6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione
#(s)-4-ethyl-4-hydroxy-1h-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione
#(s)-4-ethyl-4-hydroxy-1h-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione;(s)-(+)-camptothecin
#(s)-4-ethyl-4-hydroxy-1h-pyrano[3 inverted exclamation mark ,4 inverted exclamation mark :6,7]indolizino[1,2-b]quinoline-3,14-(4h,12h)-dione
#1h-pyrano[3',7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione, 4-ethyl-4-hydroxy-, (s)-
#4(s)-ethyl-4-hydroxy-1h-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14 (4h,12h)-dione
#4-ethyl-4-hydroxy-(4s)-3,4,12,14-tetrahydro-1h-pyrano[3'',4'':6,7]indolizino[1,2-b]quinoline-3,14-dione
#4-ethyl-4-hydroxy-1,12-dihydro-4h-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione (camptothecin or cpt)
#4-ethyl-4-hydroxy-1,12-dihydro-4h-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione (camptothecin)
#4-ethyl-4-hydroxy-1,12-dihydro-4h-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione (cpt, camptothecin)
#nsc 100880
#en300-1725804
#z1741982070
#(19s)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
#(19s)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo(11.8.0.02,11.04,9.015,20)henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
#20-(s)-camptothecine
#refchem:388854
#dtxcid8010956
#21, 22-secocamptothecin-21-oic acid lactone
#(s)-4-ethyl-4-hydroxy-1h-pyrano-(3',4':6,7)indolozino(1,2-b)quinoline-3,14(4h,12h)-dione
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d
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