Tetrodotoxin
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Description

An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order tetraodontiformes, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction. Tetrodotoxin (https://pubchem.ncbi.nlm.nih.gov/compound/Tetrodotoxin) is being investigated by Wex Pharmaceuticals for the treatment of chronic and breakthrough pain in advanced cancer patients as well as for the treatment of opioid dependence.

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peiyang
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CC-BY
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#nih-3d
#small molecules
#tetrodotoxin
#chembl507974
#4-epitetrodotoxin
#4368-28-9
#unii-3kum2721u9
#tettrodotoxin
#3kum2721u9
#tetrodonic acin
#ttx
#schembl6406675
#spheroidine
#tarichatoxin
#tetrodotoxine
#babylonia japonica toxin 1
#bjt 1
#maculotoxin
#tectin
#pft-1 toxin
#tetrodontoxin
#fugu poison
#tetrodoxin
#(1r,5r,6r,7r,9s,11s,12s,13s,14s)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol (non-preferred name)
#ccris 9328
#hsdb 3543
#9sr
#octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10ah-(1,3)dioxocino(6,5-d)pyrimidine-4,7,10,11,12-pentol
#einecs 224-458-8
#brn 0049176
#tetrodotoxin [mi]
#tetrodotoxin [inn]
#4-27-00-08206 (beilstein handbook reference)
#tetrodotoxin [who-dd]
#bdbm50344821
#zinc13780673
#(4r-(4alpha,4aalpha,5alpha,7alpha,9alpha,10alpha,10abeta,11s*,12s*))-octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10ah-(1,3)dioxocino(6,5-d) pyrimidine-4,7,10,11,12-pentol
#5,9:7,10a-dimethano-10ah-(1,3)dioxocino(6,5-d)pyrimidine-4,7,10,11,12-pentol, octahydro-12-(hydroxymethyl)-2-imino-, (4r-(4alpha,4aalpha,5alpha,7alpha,9alpha,10alpha,10abeta,11s*,12s*))-
#q-100286
#10-hydroxymethyl-5-imino-(2s)-12,13-dioxa-4,6-diazatetracyclo[7.3.1.13,11.03,8]tetradecane-1,2,7,10,14-pentaol
#10-hydroxymethyl-5-imino-(2s)-12,13-dioxa-4,6-diazatetracyclo[7.3.1.13,11.03,8]tetradecane-1,2,7,10,14-pentaolcitrate
#5,9:7,10a-dimethano-10ah-(1,3)dioxocino(6,5-d)pyrimidine-4,7,10,11,12-pentol, 2-amino-1,4,4a,5,9,10-hexahydro-12-(hydroxymethyl)-, (4r,4ar,5r,7s,9s,10s,10ar,11s,12s)-
#5,9:7,10a-dimethano-10ah-(1,3)dioxocino(6,5-d)pyrimidine-4,7,10,11,12-pentol, octahydro-12-(hydroxymethyl)-2-imino-
#5,9:7,10a-dimethano-10ah-(1,3)dioxocino(6,5-d)pyrimidine-4,7,10,11,12-pentol, octahydro-12-(hydroxymethyl)-2-imino-, (4r,4ar,5r,7s,9s,10s,10ar,11s,12s)-
#tetrodotoxina
#dtxsid10881342
#tetradotoxin
#toxin, fugu
#(1r,5r,6r,7r,9s,11s,12s,13s,14s)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.17,11.01,6]tetradec-3-ene-5,9,12,13,14-pentol
#chebi:9506
#tetrodotoxinum
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d

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Tetrodotoxin

From NIH 3D
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learning

License

CC-BY

Published

9/3/2026

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free on NIH 3D