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Description
Efavirenz is 1,4-Dihydro-2H-3,1-benzoxazin-2-one substituted at the 4 position by cyclopropylethynyl and trifluoromethyl groups (S configuration) and at the 6 position by chlorine. A non-nucleoside reverse transcriptase inhibitor with activity against HIV, it is used with other antiretrovirals for combination therapy of HIV infection. It has a role as an antiviral drug and a HIV-1 reverse transcriptase inhibitor. It is an organochlorine compound, an organofluorine compound, a benzoxazine, a member of cyclopropanes and an acetylenic compound.
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- Source creator
- Felixz
- Source license
- CC-BY
Archived copies are shared under the license shown.
View/download on NIH 3DTags
#nih-3d
#small molecules
#efavirenz
#154598-52-4
#sustiva
#stocrin
#dmp-266
#dmp 266
#(4s)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2h-3,1-benzoxazin-2-one
#eravirenz
#efavirenz, (s)-isomer
#efv
#(4s)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1h-3,1-benzoxazin-2-one
#viraday
#efavirenz teva
#l-743726
#(rac)-efavirenz
#l-743,726
#(s)-efavirenz
#(4s)-6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2h-3,1-benzoxazin-2-one
#(s)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2h-3,1-benzoxazin-2-one
#nsc-742403
#(-)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2h-3,1-benzoxazin-2-one
#(4s)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1h-3,1-benzoxazin-2-one
#je6h2o27p8
#chebi:119486
#nsc742403
#(4s)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2h-3,1-benzoxazin-2-one
#(s)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
#dsstox_cid_26029
#dsstox_rid_81298
#dsstox_gsid_46029
#(s)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2h-benzo[d][1,3]oxazin-2-one
#(s)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1h-benzo[d][1,3]oxazin-2(4h)-one
#2h-3,1-benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4s)-
#6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4s)-1,4-dihydro-2h-benzo[d][1,3]oxazin-2-one
#(-)-efavirenz
#(rac)-dmp 266; (rac)-efv; (rac)-l-743726
#smr000466351
#strocin (tm)
#sustiva (tm)
#sustiva (tn)
#cas-154598-52-4
#l 743726
#hsdb 7163
#sr-01000759360
#efavirenz [usp:inn:ban]
#unii-je6h2o27p8
#efavirenzum
#met-sdf-1.beta. & efavirenz
#1ikv
#1ikw
#efavirenz- bio-x
#ncgc00159337-02
#efavirenz, (s)
#efavirenz & plga
#mfcd05662344
#efavirenz & ifnl1
#efavirenz & ifnl2
#efavirenz & ifnl3
#efavirenz & il-29
#efavirenz [inn]
#efavirenz [jan]
#dmp-266; efavirenz
#efavirenz & il-28a
#efavirenz & il-28b
#efavirenz [mi]
#efavirenz [hsdb]
#efavirenz [usan]
#efv & interleukin 29
#efavirenz [vandf]
#efv & interleukin 28a
#efv & interleukin 28b
#efv & plga
#efavirenz [mart.]
#efavirenz [usp-rs]
#efavirenz [who-dd]
#efavirenz [who-ip]
#efv & ifnl1
#efv & ifnl2
#efv & ifnl3
#efavirenz (jan/usp/inn)
#efv & interferon lambda-1
#efv & interferon lambda-2
#efv & interferon lambda-3
#efavirenz & interleukin 29
#schembl37762
#efavirenz [ema epar]
#efavirenz & interleukin 28a
#efavirenz & interleukin 28b
#mls000759465
#mls001424087
#bidd:gt0383
#amy229
#bdbm2483
#chembl223228
#dmp266
#efv & il-28a
#efv & il-28b
#efavirenz [orange book]
#dtxsid9046029
#efavirenz, >=98% (hplc)
#efavirenz & interferon lambda-1
#efavirenz & interferon lambda-2
#efavirenz & interferon lambda-3
#efv & il-29
#gtpl11287
#telura component efavirenz
#efavirenz [usp monograph]
#atripla component efavirenz
#bcpp000245
#hms2051j08
#hms2090n16
#hms3393j08
#hms3713m14
#met-stromal cell-derived factor-1.beta. (human) & efavirenz
#efavirenzum [who-ip latin]
#2h-3,1-benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4s)-
#bcp27719
#zinc2020233
#tox21_111582
#dl-535
#s4685
#efavirenz component of atripla
#akos015894951
#tox21_111582_1
#ab21723
#bcp9000636
#ccg-101011
#db00625
#ks-5380
#nc00261
#nsc 742403
#(s)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2h-3,1-benzoxazin-2-one
#efavirenz 100 microg/ml in acetonitrile
#ncgc00159337-04
#ncgc00159337-12
#ncgc00271713-05
#ncgc00271713-08
#ac-25006
#bc164402
#hy-10572
#e0997
#c08088
#d00896
#f17329
#ab00639956-06
#ab00639956-08
#598e524
#a809555
#q422645
#j-520431
#sr-01000759360-4
#sr-01000759360-5
#efavirenz, united states pharmacopeia (usp) reference standard
#(4s)-6-chloranyl-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1h-3,1-benzoxazin-2-one
#2h-3, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4s)-
#(s)-6-chloro-4-(cyclopropyl-ethynyl)-1,4-dihydro-4-(trifluoromethyl)-2h-3,1-benzoxazine-2-one
#(s)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-(s)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2h-3,1-benzoxazin-2-one4-(trifluoromethyl)-2h-3,1-benzoxazin-2-one
#(s)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2h-3,1-ben zoxazin-2-one
#(s)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2h-3,1-benzoxazin-2-one
#en300-219935
#z2177953192
#dtxcid7026029
#(s)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo(d)(1,3)oxazin-2-one
#6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4s)-1,4-dihydro-2h-benzo(d)(1,3)oxazin-2-one
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d
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