Fenretinide
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Description

4-hydroxyphenyl retinamide is a retinoid obtained by formal condensation of the carboxy group of all-trans retinoic acid and the anilino group of 4-hydroxyaniline. Synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids. It has a role as an antioxidant and an antineoplastic agent. It is a retinoid and a monocarboxylic acid amide. It is functionally related to an all-trans-retinoic acid.

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isabella
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Public Domain
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#nih-3d
#small molecules
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#n-(4-hydroxyphenyl)retinamide
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#nsc-760419
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#4-hpr;(4-hydroxyphenyl)retinamide
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#n-(4-hydroxyphenyl)retinamide, 4-hpr
#nsc 760419
#sdccgsbi-0050606.p002
#all-trans-n-(4-hydroxyphenyl)retinamide
#dimethyl-9-(2,6,6-trimethylcyclohex-
#idi1_033889
#retinoic acid p-hydroxyanilide, >=95%
#ncgc00090752-01
#ncgc00090752-02
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#n-(4-hydroxyphenyl)-all-trans-vitamin a amide
#(2e,4e,6e,8e)-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid (4-hydroxy-phenyl)-amide
#(2e,4e,6e,8e)-n-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenamide
#(2e,4e,6e,8e)-n-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenamide
#(2e,4e,6e,8e)-n-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenamide;fenretinide
#2,6,8-nonatetraenamide, n-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl-, (all-e)-
#3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid (4-hydroxy-phenyl)-amide
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#x3d

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Fenretinide

From NIH 3D
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Category

learning

License

CC0

Published

9/2/2026

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free on NIH 3D