Vandetanib
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Description

Vandetanib is a quinazoline that is 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline bearing additional methoxy and 4-bromo-2-fluorophenylamino substituents at positions 6 and 4 respectively. Used for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It is a member of piperidines, a secondary amine, an aromatic ether, an organobromine compound, an organofluorine compound and a member of quinazolines.

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Source creator
behr
Source license
Public Domain
Archived copies are shared under the license shown.
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#nih-3d
#small molecules
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#443913-73-3
#zactima
#zd6474
#caprelsa
#n-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
#zd 6474
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#unii-yo460oq37k
#vandetanib (zd6474)
#n-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
#gnf-pf-2188
#zd-64
#azd-6474
#nsc-744325
#nsc-760766
#chembl24828
#n-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-4-quinazolinamine
#yo460oq37k
#chebi:49960
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#ncgc00167513-01
#4-[(4-bromo-2-fluorophenyl)amino]-6-methoxy-7-[(1-methyl-4-piperidyl)methoxy]quinazoline
#dsstox_cid_26681
#dsstox_rid_81816
#dsstox_gsid_46681
#4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-yl)methoxyquinazoline
#n-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine
#(4-bromo-2-fluoro-phenyl)-[6-methoxy-7-(1-methyl-piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine
#cas-443913-73-3
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#4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline
#n-(4-bromo-2-fluoro-phenyl)-6-methoxy-7-[(1-methyl-4-piperidyl)methoxy]quinazolin-4-amine
#ncgc00167513-02
#ncgc00167513-03
#ncgc00167513-04
#ncgc00167513-09
#4-bromo-2-fluoro-n-[(4e)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4(1h)-ylidene]aniline
#4-quninazolinamine, n-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-
#as-11067
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#smr002530472
#sy027438
#ft-0656736
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#913v733
#sr-00000000462
#q7914515
#sr-00000000462-2
#brd-k77625799-001-01-0
#4-quinazolinamine, n-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4- piperidinyl)methoxy)-
#6-[(4r,5s,6s,7r)-4,7-dibenzyl-3-(5-carboxypentyl)-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]hexanoic acid
#quinazolin-4-amine, n-(4-bromo-2-fluorophenyl)-6-mthoxy-7-[(1-methyl-4-piperidinyl)methoxy]-
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Vandetanib

From NIH 3D
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Category

learning

License

CC0

Published

8/31/2026

Availability

free on NIH 3D