Rosuvastatin
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Description

Rosuvastatin is a dihydroxy monocarboxylic acid that is (6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3R,5S-diastereomer). It has a role as an antilipemic drug, a xenobiotic, a CETP inhibitor, an anti-inflammatory agent, a cardioprotective agent and an environmental contaminant. It is a sulfonamide, a dihydroxy monocarboxylic acid, a member of pyrimidines, a member of monofluorobenzenes and a statin (synthetic). It is functionally related to a hept-6-enoic acid. It is a conjugate acid of a rosuvastatin(1-).

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Source creator
emckinst
Source license
Public Domain
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#nih-3d
#small molecules
#rosuvastatin
#287714-41-4
#crestor
#chembl1496
#unii-413kh5zj73
#chebi:38545
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#creston
#rosuvastatin calcium
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#x-plended
#zd-4522
#rosuvastatin (inn)
#413kh5zj73
#zd 4522
#(3r,5s,6e)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid
#(3r,5s,6e)-7-[4-(4-fluorophenyl)-2-(n-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
#(3r,5s,6e)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
#(3r,5s,e)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(n-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid
#(e)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3r,5s)-3,5-dihydroxyhept-6-enoic acid
#6-heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, (3r,5s,6e)-
#rosuvastatin [inn:ban]
#hsdb 7317
#(3r,5s,6e)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(methylsulfonyl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid
#6-heptenoic acid, 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-, (3r,5s,6e)-
#spectrum5_001695
#rosuvastatin [mi]
#rosuvastatin [hsdb]
#schembl2520
#rosuvastatin [vandf]
#bspbio_003429
#6-heptenoic acid, 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-, (3r,5s,6e)
#rosuvastatin [who-dd]
#schembl154400
#spectrum1505213
#gtpl2954
#dtxsid8048492
#bdbm18372
#chebi:93454
#hms1922n09
#zinc1535101
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#hy-17504a
#mfcd18783208
#akos000280777
#am84890
#db01098
#ncgc00178070-01
#(3r,5s,6e)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
#ac-30585
#as-12247
#sbi-0206727.p001
#s5072
#a24862
#d08492
#q415159
#brd-k82941592-001-01-3
#brd-k82941592-238-02-9
#(3r,5s)-7-[4-(4-fluorophenyl)-2-(methyl-methylsulfonylamino)-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
#(3r,5s)-trans-7-(4-(4-fluorophenyl)-6-isopropyl-2-(n-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid
#(e)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3r,5s)-3,5-dihydroxyhept-6enoic acid
#(e)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3r,5s)-3,5-dihydroxyhept-6-enoic acid
#7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid;rosuvastatin;rosuvastatin acid
#e-(7-{2-(n-methyl-n-methanesulfonylamino)-4-(4-fluorophenyl)-6-isopropyl-pyrimidin-5-yl}-(3r,5s)-3,5-dihydroxy-hept-6-enoic acid]
#e-7-[2-(n-methyl-n-methanesulfonylamino)-4-(4-fluorophenyl)-6-isopropyl-pyrimidin-5-yl]-(3r,5s)-3,5-dihydroxyhept-6-enoic acid
#fbi
#en300-370268
#en300-20321882
#(3r,5s)-7-[4-(4-fluorophenyl)-2-(n-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
#1354641-88-5
#rosuvastatina
#rosuvastatinum
#(3r,5s)-7-(4-(4-fluorophenyl)-2-(methyl-methylsulfonylamino)-6-propan-2-ylpyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid
#refchem:6205
#c10aa07
#dtxcid90820057
#rosuvastatine
#rosuvastatin acid
#3mf
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Rosuvastatin

From NIH 3D
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Category

learning

License

CC0

Published

9/2/2026

Availability

free on NIH 3D