Memantine
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Description

Memantine is a primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. It has a role as an antidepressant, an antiparkinson drug, a dopaminergic agent, a NMDA receptor antagonist and a neuroprotective agent. It is a primary aliphatic amine and a member of adamantanes. It is a conjugate base of a memantinium(1+). It derives from a hydride of an adamantane.

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Source creator
nevitdilmen
Source license
Public Domain
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#nih-3d
#small molecules
#memantine
#3,5-dimethyladamantan-1-amine
#19982-08-2
#memantina
#ebixa
#namenda
#1-amino-3,5-dimethyladamantane
#memantinum
#memantin
#memantinum [inn-latin]
#1,3-dimethyl-5-adamantanamine
#3,5-dimethyl-1-adamantanamine
#memantine [inn]
#memantina [inn-spanish]
#3,5-dimethyl-1-aminoadamantane
#3,5-dimethyl-1-adamantylamine
#3,5-dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
#tricyclo[3.3.1.13,7]decan-1-amine, 3,5-dimethyl-
#d-145
#drg-0267
#chembl807
#w8o17sjf3t
#chebi:64312
#memantine (inn)
#nsc-757843
#alzantin
#ncgc00015705-04
#dsstox_cid_25174
#dsstox_rid_80723
#dsstox_gsid_45174
#d 145
#nemdatine
#memantine [inn:ban]
#cas-19982-08-2
#hsdb 7327
#3,5-dimethyltricyclo[3.3.1.1~3,7~]decan-1-amine
#unii-w8o17sjf3t
#dmaa [antiparkinson agent]
#3,5-dimethyladamantanylamine
#retyliumtosylate
#1,3-dimethyl-5-aminoadamantane
#drg 0267
#exiba (tn)
#spectrum_000607
#memantine [mi]
#memantine [hsdb]
#prestwick0_000978
#prestwick1_000978
#prestwick2_000978
#prestwick3_000978
#spectrum2_001408
#spectrum3_000923
#spectrum4_001022
#spectrum5_001355
#memantine [vandf]
#cbmicro_020348
#biomol-nt_000209
#memantine [who-dd]
#schembl2688
#lopac0_000861
#oprea1_480562
#bspbio_001015
#kbiogr_001543
#kbioss_001087
#divk1c_000068
#spbio_001456
#spbio_002926
#1-amino-3,5-dimethyladamantan
#bpbio1_001117
#bpbio1_001270
#gtpl4253
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#schembl13213676
#hms500d10
#kbio1_000068
#kbio2_001087
#kbio2_003655
#kbio2_006223
#kbio3_001926
#1-amino-3,5-dimethyl adamantane
#1-amino-3,5-dimethyl-adamantane
#tricyclo(3.3.1.1(3,7))decan-1-amine, 3,5-dimethyl-
#ninds_000068
#3,5-dimethyl-adamantan-1-ylamine
#albb-013872
#bcp29702
#tox21_110199
#3,5-dimethyl-1-aminoadamantane hcl
#bbl000737
#bdbm50062599
#stk520682
#akos000113995
#akos015953276
#akos016340748
#tox21_110199_1
#ccg-204092
#db01043
#ds-3152
#nsc 757843
#sdccgsbi-0020417.p005
#idi1_000068
#ncgc00015705-03
#ncgc00015705-05
#ncgc00015705-07
#ncgc00015705-09
#ncgc00015705-16
#ncgc00024782-02
#ncgc00024782-03
#d145 pound>>d 145 pound>>d-145
#sbi-0020417.p004
#ab00053600
#bb 0216388
#eu-0053634
#ft-0649142
#d08174
#d94592
#ab00053600-13
#ab00053600_14
#ab00053600_15
#a814131
#q412189
#3,5-dimethyltricyclo(3.3.1.1(sup 3,7))decan-1-amine
#tricyclo(3.3.1.1(sup 3,7))decan-1-amine, 3,5-dimethyl-
#en300-103626
#dtxcid3025174
#tricyclo(3.3.1.13,7)decan-1-amine, 3,5-dimethyl-
#n06dx01
#refchem:5992
#3mf
#blend
#fbx
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#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d

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Memantine

From NIH 3D
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Category

learning

License

CC0

Published

9/2/2026

Availability

free on NIH 3D