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Description
Temozolomide is an imidazotetrazine that is 3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine which is substituted at positions 3, 4, and 8 by methyl, oxo, and carboxamide groups, respectively. A prodrug for MTIC (5-(3-methyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide, formed by spontaneous hydrolysis of temozolomide in the body), it is used as an oral alkylating agent for the treatment of newly diagnosed malignant glioblastoma multiforme (concomitantly with radiotherapy) and malignant melanoma. It has a role as an alkylating agent, an antineoplastic agent and a prodrug. It is a monocarboxylic acid amide, an imidazotetrazine and a triazene derivative.
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- adamant628
- Source license
- Public Domain
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#nih-3d
#small molecules
#temozolomide
#85622-93-1
#temodar
#methazolastone
#temodal
#3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
#ccrg-81045
#temozolamide
#temozolomidum
#temozolodida
#sch 52365
#temozolomidum [latin]
#temozolodida [spanish]
#ccrg 81045
#nsc 362856
#sch-52365
#m&b 39831
#m&b-39831
#nsc-362856
#ccris 8996
#mb 39831
#8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3h)-one
#m & b 39831
#brn 5547136
#m-39831
#3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide
#3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide
#3-methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide
#nsc362856
#3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
#chembl810
#mls002701861
#yf1k15m17y
#chebi:72564
#mk-7365
#imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-
#tmz
#ncgc00167429-01
#3-methyl-4-oxo-3h,4h-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide
#dsstox_cid_23714
#dsstox_rid_80068
#dsstox_gsid_43714
#3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide
#3-methyl-4-oxo-3,4-dihydroimidazo-[5,1-d][1,2,3,5]tetrazine-8-carboxamide
#3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide.
#3-methyl-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid amide
#smr000466338
#temodal (tn)
#temodar (tn)
#cas-85622-93-1
#temozolomide, vetranal(tm), analytical standard
#sr-01000759347
#temozolomida
#unii-yf1k15m17y
#temozolomide (jan/usan/inn)
#temozolomide [usan:inn:ban]
#imidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-
#mfcd00866492
#temozolomide- bio-x
#temozolomide [mi]
#temozolomide [inn]
#temozolomide [jan]
#temodar (tn) (schering)
#temozolomide [usan]
#schembl3739
#4-methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide
#temozolomide [vandf]
#temozolomide [mart.]
#mls000759447
#mls001424028
#bidd:gt0204
#temozolomide [usp-rs]
#temozolomide [who-dd]
#gtpl7301
#temozolomide [ema epar]
#dtxsid5043714
#temozolomide, >=98% (hplc)
#hms2051o12
#hms2090b08
#hms2232n13
#hms3264i14
#hms3269p05
#hms3372k13
#hms3393o12
#hms3413d06
#hms3654n05
#hms3677d06
#hms3713h16
#pharmakon1600-01502289
#temozolomide [orange book]
#temozolomide [ep monograph]
#3-methyl-4-oxo-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
#albb-021358
#bcp03692
#zinc1482184
#temozolomide [usp monograph]
#tox21_112433
#ac-758
#bdbm50034562
#dl-190
#nsc759883
#s1237
#stk623541
#3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
#3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetraazine-8-carboxamide
#akos005557098
#tox21_112433_1
#ccg-100870
#cs-0943
#db00853
#ks-1216
#nc00120
#nsc-759883
#imidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-
#ncgc00167429-02
#ncgc00167429-04
#ncgc00167429-05
#bp-25388
#bt164447
#hy-17364
#nci60_003316
#bcp0726000154
#temozolomide 100 microg/ml in acetonitrile
#am20110227
#ft-0630936
#ft-0674845
#sw197500-4
#t2744
#d06067
#ab00639915-06
#ab00639915-08
#ab00639915-09
#ab00639915_10
#ab00639915_11
#622t931
#a841386
#q425088
#q-201786
#sr-01000759347-4
#sr-01000759347-5
#brd-k32107296-001-04-5
#3-methyl-4-oxo-8-imidazo[5,1-d][1,2,3,5]tetrazinecarboxamide
#temozolomide, united states pharmacopeia (usp) reference standard
#3-methyl-4-oxidanylidene-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
#3-methyl-8-aminocarbonyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3h)-one
#imidazo[5,2,3,5-tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-
#{imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide,} 3, 4-dihydro-3-methyl-4-oxo-
#temozolomide, pharmaceutical secondary standard; certified reference material
#3-methyl-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid amide (temozolomide)
#3-methyl-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid amide(temozolomide)
#8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3h)-one
#3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-as-tetrazine-8-carboxamide
#en300-122324
#z1201620684
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d
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