Description

Tetrahydrobiopterin (https://pubchem.ncbi.nlm.nih.gov/compound/Tetrahydrobiopterin) or BH4 is a cofactor in the synthesis of nitric oxide (https://pubchem.ncbi.nlm.nih.gov/compound/nitric%20oxide). It is also essential in the conversion of phenylalanine (https://pubchem.ncbi.nlm.nih.gov/compound/phenylalanine) to tyrosine (https://pubchem.ncbi.nlm.nih.gov/compound/tyrosine) by the enzyme phenylalanine (https://pubchem.ncbi.nlm.nih.gov/compound/phenylalanine)-4-hydroxylase; the conversion of tyrosine (https://pubchem.ncbi.nlm.nih.gov/compound/tyrosine) to L-dopa (https://pubchem.ncbi.nlm.nih.gov/compound/L-dopa) by the enzyme tyrosine (https://pubchem.ncbi.nlm.nih.gov/compound/tyrosine) hydroxylase; and conversion of tryptophan (https://pubchem.ncbi.nlm.nih.gov/compound/tryptophan) to 5-hydroxytryptophan (https://pubchem.ncbi.nlm.nih.gov/compound/5-hydroxytryptophan) via tryptophan (https://pubchem.ncbi.nlm.nih.gov/compound/tryptophan) hydroxylase. [Wikipedia]