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Description
Exemestane is a 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer. It has a role as an antineoplastic agent, a xenobiotic, an EC 1.14.14.14 (aromatase) inhibitor and an environmental contaminant. It is a 17-oxo steroid and a 3-oxo-Delta(1),Delta(4)-steroid. It derives from a hydride of an androstane.
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- Source creator
- nevitdilmen
- Source license
- Public Domain
Archived copies are shared under the license shown.
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#nih-3d
#small molecules
#exemestane
#107868-30-4
#aromasin
#6-methyleneandrosta-1,4-diene-3,17-dione
#exemestano
#exemestanum
#exemestance
#fce-24304
#aromasil
#aromasine
#fce 24304
#exemestanum [inn-latin]
#exemestano [inn-spanish]
#6-methylene-androsta-1,4-diene-3,17-dione
#androsta-1,4-diene-3,17-dione, 6-methylene-
#fce24304
#pnu-155971
#ny22hmq4bx
#chebi:4953
#(8r,9s,10r,13s,14s)-10,13-dimethyl-6-methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3h-cyclopenta[a]phenanthrene-3,17(6h)-dione
#(8r,9s,10r,13s,14s)-10,13-dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6h-cyclopenta[a]phenanthrene-3,17(10h,14h)-dione
#(8r,9s,10r,13s,14s)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione
#nsc713563
#nsc-758907
#exe
#dsstox_cid_3037
#dsstox_rid_76844
#dsstox_gsid_23037
#6-methylideneandrosta-1,4-diene-3,17-dione
#exemestane [usan:inn:ban]
#nikidess
#(8alpha,10alpha,13alpha)-6-methylideneandrosta-1,4-diene-3,17-dione
#aromasin (tn)
#smr000466314
#cas-107868-30-4
#hsdb 7463
#curator_000009
#unii-ny22hmq4bx
#exemestane (jan/usp/inn)
#ccris 9351
#ncgc00095289-01
#exemestane [inn]
#exemestane; aromasin
#exemestane, aromasin
#pnu 155971
#exemestane [mi]
#exemestane [jan]
#exemestane [hsdb]
#exemestane [usan]
#exemestane [vandf]
#exemestane [mart.]
#schembl6215
#aromasin (pharmacia upjohn)
#exemestane [usp-rs]
#exemestane [who-dd]
#exemestane(fce 24304)
#mls000759419
#mls001424062
#gtpl7073
#6-methylenandrosta-1,17-dione
#chembl1200374
#dtxsid5023037
#exemestane [orange book]
#exemestane, >=98% (hplc)
#exemestane [ep monograph]
#bcpp000235
#exemestane [usp monograph]
#hms2051j04
#hms3713h12
#bcp23353
#zinc3973334
#tox21_111499
#bdbm50398447
#pnu155971
#s1196
#akos015840113
#akos015895161
#tox21_111499_1
#ac-2171
#bcp9000676
#ccg-100995
#cs-1766
#db00990
#ks-5136
#nc00245
#nsc 758907
#nsc-713563
#ncgc00271596-03
#6-methylenandrost-1,4-dien-3,17-dione
#as-31053
#cpd000466314
#hy-13632
#bcp0726000226
#6-methylen-androst-1,4-diene-3,17-dione
#e0941
#c08162
#d00963
#ab00639936-06
#ab00639936-08
#ab00639936-09
#ab00639936-10
#ab00639936_11
#868e304
#a801772
#q418819
#sr-01000759393
#sr-01000759393-4
#brd-k33425534-001-12-5
#exemestane, european pharmacopoeia (ep) reference standard
#exemestane, united states pharmacopeia (usp) reference standard
#exemestane, pharmaceutical secondary standard; certified reference material
#exemestane for system suitability, european pharmacopoeia (ep) reference standard
#(1s,2r,10r,11s,15s)-2,15-dimethyl-8-methylidenetetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,14-dione
#exm
#dtxcid003037
#examestane
#(1s,2r,10r,11s,15s)-2,15-dimethyl-8-methylidenetetracyclo(8.7.0.0^(2,7).0^(11,15))heptadeca-3,6-diene-5,14-dione
#(8r,9s,10r,13s,14s)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta(a)phenanthrene-3,17-dione
#refchem:57964
#l02bg06
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d
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