Aspartame
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Description

Aspartame is a dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate. Commonly used as an artificial sweetener. It has a role as a micronutrient, a xenobiotic, a sweetening agent, a nutraceutical, an EC 3.1.3.1 (alkaline phosphatase) inhibitor, an apoptosis inhibitor and an environmental contaminant. It is a methyl ester, a carboxylic acid and a dipeptide. It is functionally related to a L-aspartic acid and a methyl L-phenylalaninate. It is a tautomer of an aspartame zwitterion.

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Source creator
Nick Weber
Source license
Public Domain
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#nih-3d
#small molecules
#aspartame
#asp-phe methyl ester
#asp-phe-ome
#aspartam
#aspartamo
#22839-47-0
#aspartylphenylalanine methyl ester
#nutrasweet
#canderel
#l-aspartyl-l-phenylalanine methyl ester
#aspartamum
#equal
#sweet dipeptide
#methyl aspartylphenylalanate
#dipeptide sweetener
#pal sweet
#h-asp-phe-ome
#1-methyl n-l-alpha-aspartyl-l-phenylalanate
#tri-sweet
#sladex
#zero-cal
#methyl l-alpha-aspartyl-l-phenylalaninate
#sc-18862
#3-amino-n-(alpha-methoxycarbonylphenethyl) succinamic acid
#(s)-3-amino-4-(((s)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoic acid
#chebi:2877
#n-l-alpha-aspartyl-l-phenylalanine 1-methyl ester
#3-amino-n-(alpha-carboxyphenethyl)succinamic acid n-methyl ester
#aspartame (e951)
#ins no.951
#(3s)-3-amino-4-[[(2s)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
#n-l-alpha-aspartyl-l-phenylalanine methyl ester
#nsc-758953
#ins-951
#z0h242bbr1
#(s)-3-amino-4-((s)-1-methoxy-1-oxo-3-phenylpropan-2-ylamino)-4-oxobutanoic acid
#l-aspartyl-l-phenylalanyl methyl ester
#n-l-alpha-aspartyl l-phenylalanine 1-methyl ester
#ncgc00091104-02
#dsstox_cid_107
#e 951
#e-951
#mfcd00002724
#dsstox_rid_75371
#dsstox_gsid_20107
#sanecta
#aspartam [inn-french]
#aspartame, l,l-alpha-
#aspartamum [inn-latin]
#aspartamo [inn-spanish]
#smr000471870
#cas-22839-47-0
#ccris 5456
#sc 18862
#hsdb 3915
#methyl l-aspartyl-l-phenylalanine
#einecs 245-261-3
#l-phenylalanine, n-l-.alpha.-aspartyl-, 1-methyl ester
#methyl l-alpha-aspartyl-l-phenylalanate
#unii-z0h242bbr1
#aminosweet
#l-phenylalanine, n-l-alpha-aspartyl-, 1-methyl ester
#palsweet diet
#methyl n-l-alpha-aspartyl-l-phenylalaninate
#1-methyl n-l-alpha-aspartyl-l-phenylalanine
#aspartame [usan:inn:ban:nf]
#ncgc00095160-01
#df-ome
#aspartame (nf/inn)
#n-(l-a-aspartyl)-l-phenylalanine methyl ester
#aspartame [fcc]
#aspartame [inn]
#aspartame [ii]
#aspartame [mi]
#aspartame [fhfi]
#aspartame [hsdb]
#aspartame [inci]
#aspartame [usan]
#spectrum2_001706
#spectrum3_001949
#aspartame [vandf]
#aspartame [mart.]
#epitope id:164026
#3-amino-n-(alpha-carboxyphenethyl)succinamic acid n-methyl ester, stereoisomer
#aspartame [usp-rs]
#aspartame [who-dd]
#schembl3636
#succinamic acid, 3-amino-n-(alpha-carboxyphenethyl)-, n-methyl ester, stereoisomer
#bspbio_003549
#mls001066421
#mls001306461
#aspartame, analytical standard
#spectrum1505306
#l-phenylalanine, l-alpha-aspartyl-, 2-methyl ester
#spbio_001692
#chembl171679
#aspartame [ep monograph]
#dtxsid0020107
#asp-phe methyl ester, >=98%
#kbio3_002839
#aspartyl-phenylalanine methyl ester
#hms1922b16
#hms2093b05
#hms2233d15
#pharmakon1600-01505306
#hy-b0361
#zinc1532132
#tox21_111080
#tox21_111459
#tox21_202315
#tox21_302965
#ccg-39444
#nsc758953
#s2036
#akos015920055
#tert-butyln-(3-formylphenyl)carbamate
#tox21_111080_1
#am84801
#aspartame 1000 microg/ml in methanol
#db00168
#nsc 758953
#alpha-aspartyl-phenylalanine methyl ester
#l-aspartyl-l-phenyl-alanine methyl ester
#ncgc00091104-01
#ncgc00091104-03
#ncgc00091104-04
#ncgc00091104-05
#ncgc00095160-03
#ncgc00256407-01
#ncgc00259864-01
#7421-84-3
#ac-12293
#as-13889
#e951
#l-aspartyl-l-3-phenylalanine methyl ester
#sbi-0206757.p001
#asp-phe methyl ester, >=99.0% (hplc)
#a0997
#am20060556
#sw219179-1
#alpha-l-aspartyl-l-phenylalanine methyl ester
#l-aspartyl-l-phenylalanine methyl ester, 96%
#39a470
#d02381
#ab00376622_08
#ab00376622_09
#a816383
#q182040
#sr-05000001682
#j-502447
#sr-05000001682-1
#brd-k78841970-001-06-2
#aspartame, european pharmacopoeia (ep) reference standard
#aspartame, united states pharmacopeia (usp) reference standard
#(s)-3-amino-n-((s)-1-methoxycarbonyl-2-phenyl-ethyl)-succinamic acid
#aspartame, pharmaceutical secondary standard; certified reference material
#(3s)-3-amino-3-{[(2s)-1-methoxy-1-oxo-3-phenylpropan-2-yl]carbamoyl}propanoic acid
#(s)-3-amino-4-(((s)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoicacid
#3-amino-4-[(1-carboxy-2-phenyl-ethyl)-methyl-amino]-4-oxo-butanoic acid;n-l-alpha-aspartyl-l-phenylalanine methyl ester
#l-alpha-aspartyl-l-phenylalanine 2-methyl ester
#3mf
#blend
#fbx
#glb
#jpg
#mtl
#obj
#ply
#png
#stl
#wrl
#x3d

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Aspartame

From NIH 3D
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Category

learning

License

CC0

Published

10/15/2026

Availability

free on NIH 3D